Iranian Journal of Radiology

Published by: Kowsar

Clinical and Radiological Differences Between Fistular and Non-Fistular Idiopathic Granulomatous Mastitis

Necla Eryilmaz 1 , Mehmet Ali Eryilmaz 2 , Serdar Arslan 3 , * , Ibrahim Solak 4 , Selma Pekgor 4 , Aysegul Altunkeser 3 and Ethem Omeroglu 5
Authors Information
1 Department of Dermatology, K.T.O. Karatay University Medical Faculty, Konya, Turkey
2 Department of General Surgery, Konya Training and Research Hospital, University of Health Science, Konya, Turkey
3 Department of Radiology, Konya Training and Research Hospital, University of Health Sciences, Konya, Turkey
4 Department of Family Medicine, Training and Research Hospital, Medical Sciences University, Konya, Turkey
5 Department of Pathology, Konya Training and Research Hospital, University of Health Sciences, Konya, Turkey
Article information
  • Iranian Journal of Radiology: 16 (1); e79333
  • Published Online: December 29, 2018
  • Article Type: Research Article
  • Received: May 19, 2018
  • Revised: December 4, 2018
  • Accepted: December 8, 2018
  • DOI: 10.5812/iranjradiol.79333

To Cite: Eryilmaz N, Eryilmaz M A, Arslan S, Solak I, Pekgor S, et al. Clinical and Radiological Differences Between Fistular and Non-Fistular Idiopathic Granulomatous Mastitis, Iran J Radiol. Online ahead of Print ; 16(1):e79333. doi: 10.5812/iranjradiol.79333.

Copyright © 2018, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Ozel L, Unal A, Unal E, Kara M, Erdogdu E, Krand O, et al. Granulomatous mastitis: Is it an autoimmune disease? Diagnostic and therapeutic dilemmas. Surg Today. 2012;42(8):729-33. doi: 10.1007/s00595-011-0046-z. [PubMed: 22068681].
  • 2. Gautier N, Lalonde L, Tran-Thanh D, El Khoury M, David J, Labelle M, et al. Chronic granulomatous mastitis: Imaging, pathology and management. Eur J Radiol. 2013;82(4):e165-75. doi: 10.1016/j.ejrad.2012.11.010. [PubMed: 23200627].
  • 3. Lai EC, Chan WC, Ma TK, Tang AP, Poon CS, Leong HT. The role of conservative treatment in idiopathic granulomatous mastitis. Breast J. 2005;11(6):454-6. doi: 10.1111/j.1075-122X.2005.00127.x. [PubMed: 16297091].
  • 4. Aldaqal SM. Idiopathic granulomatous mastitis. Clinical presentation, radiological features and treatment. Saudi Med J. 2004;25(12):1884-7. [PubMed: 15711659].
  • 5. Hovanessian Larsen LJ, Peyvandi B, Klipfel N, Grant E, Iyengar G. Granulomatous lobular mastitis: Imaging, diagnosis, and treatment. AJR Am J Roentgenol. 2009;193(2):574-81. doi: 10.2214/AJR.08.1528. [PubMed: 19620458].
  • 6. Tuli R, O'Hara BJ, Hines J, Rosenberg AL. Idiopathic granulomatous mastitis masquerading as carcinoma of the breast: a case report and review of the literature. Int Semin Surg Oncol. 2007;4:21. doi: 10.1186/1477-7800-4-21. [PubMed: 17662130]. [PubMed Central: PMC1949402].
  • 7. Kok KY, Telisinghe PU. Granulomatous mastitis: Presentation, treatment and outcome in 43 patients. Surgeon. 2010;8(4):197-201. doi: 10.1016/j.surge.2010.02.002. [PubMed: 20569938].
  • 8. Sakurai K, Fujisaki S, Enomoto K, Amano S, Sugitani M. Evaluation of follow-up strategies for corticosteroid therapy of idiopathic granulomatous mastitis. Surg Today. 2011;41(3):333-7. doi: 10.1007/s00595-009-4292-2. [PubMed: 21365412].
  • 9. Altintoprak F, Kivilcim T, Yalkin O, Uzunoglu Y, Kahyaoglu Z, Dilek ON. Topical steroids are effective in the treatment of idiopathic granulomatous mastitis. World J Surg. 2015;39(11):2718-23. doi: 10.1007/s00268-015-3147-9. [PubMed: 26148520].
  • 10. Ahmed YS, Abd El Maksoud W. Evaluation of therapeutic mammoplasty techniques in the surgical management of female patients with idiopathic granulomatous mastitis with mild to moderate inflammatory symptoms in terms of recurrence and patients' satisfaction. Breast Dis. 2016;36(1):37-45. doi: 10.3233/BD-150198. [PubMed: 27177342].
  • 11. Li S, Grant CS, Degnim A, Donohue J. Surgical management of recurrent subareolar breast abscesses: Mayo Clinic experience. Am J Surg. 2006;192(4):528-9. doi: 10.1016/j.amjsurg.2006.06.010. [PubMed: 16978967].
  • 12. Handa P, Leibman AJ, Sun D, Abadi M, Goldberg A. Granulomatous mastitis: Changing clinical and imaging features with image-guided biopsy correlation. Eur Radiol. 2014;24(10):2404-11. doi: 10.1007/s00330-014-3273-z. [PubMed: 24962828].
  • 13. Pluguez-Turull CW, Nanyes JE, Quintero CJ, Alizai H, Mais DD, Kist KA, et al. Idiopathic granulomatous mastitis: Manifestations at multimodality imaging and pitfalls. Radiographics. 2018;38(2):330-56. doi: 10.1148/rg.2018170095. [PubMed: 29528819].
  • 14. Cho SH, Park SH. Mimickers of breast malignancy on breast sonography. J Ultrasound Med. 2013;32(11):2029-36. doi: 10.7863/ultra.32.11.2029. [PubMed: 24154908].
  • 15. Ozturk M, Mavili E, Kahriman G, Akcan AC, Ozturk F. Granulomatous mastitis: Radiological findings. Acta Radiol. 2007;48(2):150-5. doi: 10.1080/02841850601128975. [PubMed: 17354134].
  • 16. Aghajanzadeh M, Hassanzadeh R, Alizadeh Sefat S, Alavi A, Hemmati H, Esmaeili Delshad MS, et al. Granulomatous mastitis: Presentations, diagnosis, treatment and outcome in 206 patients from the north of Iran. Breast. 2015;24(4):456-60. doi: 10.1016/j.breast.2015.04.003. [PubMed: 25935828].
  • 17. Yildiz S, Aralasmak A, Kadioglu H, Toprak H, Yetis H, Gucin Z, et al. Radiologic findings of idiopathic granulomatous mastitis. Med Ultrason. 2015;17(1):39-44. doi: 10.11152/mu.2013.2066.171.rfm. [PubMed: 25745656].
  • 18. Skandarajah A, Marley L. Idiopathic granulomatous mastitis: A medical or surgical disease of the breast? ANZ J Surg. 2015;85(12):979-82. doi: 10.1111/ans.12929. [PubMed: 25424519].
  • 19. Seo HR, Na KY, Yim HE, Kim TH, Kang DK, Oh KK, et al. Differential diagnosis in idiopathic granulomatous mastitis and tuberculous mastitis. J Breast Cancer. 2012;15(1):111-8. doi: 10.4048/jbc.2012.15.1.111. [PubMed: 22493637]. [PubMed Central: PMC3318162].
  • 20. Akcan A, Akyildiz H, Deneme MA, Akgun H, Aritas Y. Granulomatous lobular mastitis: A complex diagnostic and therapeutic problem. World J Surg. 2006;30(8):1403-9. doi: 10.1007/s00268-005-0476-0. [PubMed: 16847715].
  • 21. Patel RA, Strickland P, Sankara IR, Pinkston G, Many WJ, Rodriguez M. Idiopathic granulomatous mastitis: Case reports and review of literature. J Gen Intern Med. 2010;25(3):270-3. doi: 10.1007/s11606-009-1207-2. [PubMed: 20013067]. [PubMed Central: PMC2839326].
  • 22. Boufettal H, Essodegui F, Noun M, Hermas S, Samouh N. Idiopathic granulomatous mastitis: A report of twenty cases. Diagn Interv Imaging. 2012;93(7-8):586-96. doi: 10.1016/j.diii.2012.04.028. [PubMed: 22677299].
  • 23. Han BK, Choe YH, Park JM, Moon WK, Ko YH, Yang JH, et al. Granulomatous mastitis: Mammographic and sonographic appearances. AJR Am J Roentgenol. 1999;173(2):317-20. doi: 10.2214/ajr.173.2.10430126. [PubMed: 10430126].
  • 24. Yilmaz E, Lebe B, Usal C, Balci P. Mammographic and sonographic findings in the diagnosis of idiopathic granulomatous mastitis. Eur Radiol. 2001;11(11):2236-40. doi: 10.1007/s003300100965. [PubMed: 11702165].
  • 25. Aslan H, Pourbagher A, Colakoglu T. Idiopathic granulomatous mastitis: Magnetic resonance imaging findings with diffusion MRI. Acta Radiol. 2016;57(7):796-801. doi: 10.1177/0284185115609804. [PubMed: 26508792].
  • 26. Dursun M, Yilmaz S, Yahyayev A, Salmaslioglu A, Yavuz E, Igci A, et al. Multimodality imaging features of idiopathic granulomatous mastitis: Outcome of 12 years of experience. Radiol Med. 2012;117(4):529-38. doi: 10.1007/s11547-011-0733-2. [PubMed: 22020426].

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments