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The Importance of Diffusion Weighted Imaging in Breast MRI

AUTHORS

Maryam Noori 1 , * , Bahareh Siahlou 1 , Hamidreza Salighehrad 1 , Anahita Fathi 1 , Mohammad Fathi 1

1 MD, Radiologist, Paytakht

How to Cite: Noori M, Siahlou B, Salighehrad H, Fathi A, Fathi M. The Importance of Diffusion Weighted Imaging in Breast MRI, Iran J Radiol. Online ahead of Print ; 14(Special Issue):e47964. doi: 10.5812/iranjradiol.47964.

ARTICLE INFORMATION

Iranian Journal of Radiology: 14 (Special Issue); e47964
Published Online: April 12, 2017
Article Type: Abstract
Received: December 20, 2016
Accepted: February 7, 2017
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Abstract

Objectives: The aim of this study was to evaluate the value of diffusion weighted imaging in Diffusion weighted imaging in distinguishing between in benign and malignant breast lesion

Methods: There were 37 female patients with 47 lesions. Sixty seven female subjectd (40 mean age ) ,age ranges 17-69 , with histopathologically proven breast lesions underwent DWI of breasts with a single shot echo planar imaging (EPI )sequence .the computed mean apparent diffusion cofficients (ADCs) of the breasts lesion and cell density were then correlated.

Results: The ADC varied substantially between benign breast lesions ((1.52 0.26) 10 -3 mm2 / second). And malignant breast lesions ((0.94 0.21) 10 -3 mm2 / second) .The AUC with ROC analysis was 0.896 and the threshold for ADC was 1.17 10-3 mm2 /second with a sensitivity and specificity of 90% and 85%, respectively. The mean ADC of malignant breast lesions was statistically lower for benign lesions (P value less than 0.01)

Conclusions: The ADC would be a effective parameter in distinguishing between malignant and benign breast lesions.

Keywords

© 2017, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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