Intraosseous Neurofibroma and Concurrent Involvement of the Mandible, Maxilla and Orbit: Report of a Case

AUTHORS

Zahra Dalili 1 , * , Gholamhossein Adham 2

1 Department of Maxillofacial Radiology, Dental School, Guilan University of Medical Sciences, Dalili@gums.ac.ir, Iran

2 Department of Maxillofacial Surgery, Dental School, Guilan University Of Medical Sciences, Iran

How to Cite: Dalili Z , Adham G . Intraosseous Neurofibroma and Concurrent Involvement of the Mandible, Maxilla and Orbit: Report of a Case, Iran J Radiol. Online ahead of Print ; 9(1):45-9. doi: 10.5812/iranjradiol.6684.

ARTICLE INFORMATION

Iranian Journal of Radiology: 9 (1); 45-9
Published Online: March 25, 2012
Article Type: Case Report
Received: December 27, 2010
Accepted: December 21, 2011
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Abstract

Neurofibroma is an autosomal dominant disorder which has major criteria such as hyperpigmentation (cafe-au lait spots), cutaneous and subcutaneous tumors and bone deformities. In this report, a case of multifocal intraosseous neurofibroma in a 16-year-old male with right facial asymmetry, multiple unerupted maxillary posterior teeth and a previous history of infratemporal and orbital neurofibroma is presented. The majority of reported cases occurred in the posterior portion of the mandible and a limited number in the maxilla. Cone beam CT (CBCT) was performed for better evaluation of the extension and form of the maxillary and mandibular lesions. This report presents a rare situation of simultaneous peripheral neurofibromatosis (NF) and multifocal intraosseous NF in the mandible, maxilla and orbits and also focuses on advanced imaging findings of bony and soft tissue neurofibroma.

Keywords

Neurofibroma S100 Proteins Magnetic Resonance Imaging Cone-Beam Computed Tomography

© 2012, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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