Breast Ductal Carcinoma in Situ: Morphologic and Kinetic MRI Findings

AUTHORS

Mirjan M. Nadrljanski 1 , * , Biljana B. Markovi? 3 , Zorica ?. Miloevi? 3

1 Department of Diagnostic Imaging, Institute of Oncology and Radiology of Serbia (IORS), Serbia

3 Department of Radiology, Faculty of Medicine, University of Belgrade, Serbia

How to Cite: Nadrljanski M M, Markovi? B B, Miloevi? Z ?. Breast Ductal Carcinoma in Situ: Morphologic and Kinetic MRI Findings, Iran J Radiol. Online ahead of Print ; 10(2):99-102. doi: 10.5812/iranjradiol.4876.

ARTICLE INFORMATION

Iranian Journal of Radiology: 10 (2); 99-102
Published Online: May 19, 2013
Article Type: Brief Report
Received: March 15, 2012
Accepted: October 5, 2012
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Abstract

Background: Adequate diagnosis of ductal carcinoma in situ (DCIS) could lead to efficacious treatment. Due to the fact that DCIS lesions can progress to invasive carcinomas and that the sensitivity of the standard examination mammography is between 70 and 80%, use of a more sensitive diagnostic tool was needed. In detection of DCIS, contrast-enhanced magnetic resonance imaging (CE-MRI) has the sensitivity up to 96%.

Objectives: Morphological features and kinetic parameters were evaluated to define the most regular morphological, kinetic and morpho-kinetic patterns on MRI assessment of breast ductal carcinoma in situ (DCIS).

Patients and Methods: We retrospectively assessed eighteen patients with 23 histologically confirmed lesions (mean age, 52.4 10.5 years). All patients were clinically and mammographically examined prior to MRI examination.

Results: DCIS appeared most frequently as non-mass-like lesions (12 lesions, 52.17%). The differences in the frequency of lesion types were statistically significant (P<0.05). The following morphological patterns were detected: A: no specific morphologic features, B: linear/branching enhancement, C: focal mass-like enhancement, D: segmental enhancement, E: segmental enhancement in triangular shape, F: diffuse enhancement, G: regional heterogeneous enhancement in one quadrant not conforming to duct distribution and H: dotted or granular type of enhancement with patchy distribution. The difference in the frequency of the proposed patterns was statistically significant (P<0.05). There were eight lesions with mass enhancement, and six with segmental lesions: regional and triangular. There was no statistically significant difference in the frequency of enhancement curve types (P>0.05). There was no significant difference in the frequency of morpho-kinetic patterns.

Conclusion: Non-mass-like lesions, lesions with focal or segmental distribution, with a plateau enhancement curve type were the most frequent findings of DCIS lesions on MRI.

Keywords

Carcinoma, Intraductal, Non infiltrating Magnetic Resonance Imaging Breast Neoplasms Image Enhancement Gadolinium DTPA

© 2013, Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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