Iranian Journal of Radiology

Published by: Kowsar

Radiation Dose and Image Quality Assessment of the Bolus Timing Method for CT Angiography

Myeong Seong Kim 1 , Jong-Woong Lee 2 , Sun Geun Kim 3 and Dae Cheol Kweon 4 , *
Authors Information
1 Department of Radiology, The Korean National Cancer Center, Goyang, Republic of Korea
2 Department of Radiology, Kyung Hee University Hospital at Gang-dong, Seoul, Republic of Korea
3 Department of Radiological Technology, Baekseok Culture University, Cheonan, Republic of Korea
4 Department of Radiological Science, Shinhan University, Uijeongbu, Republic of Korea
Article information
  • Iranian Journal of Radiology: April 2017, 14 (2); e31918
  • Published Online: August 20, 2016
  • Article Type: Research Article
  • Received: September 15, 2015
  • Revised: October 21, 2015
  • Accepted: October 29, 2015
  • DOI: 10.5812/iranjradiol.31918

To Cite: Seong Kim M, Lee J, Geun Kim S, Cheol Kweon D. Radiation Dose and Image Quality Assessment of the Bolus Timing Method for CT Angiography, Iran J Radiol. 2017 ; 14(2):e31918. doi: 10.5812/iranjradiol.31918.

Copyright © 2016, Tehran University of Medical Sciences and Iranian Society of Radiology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Wintersperger B, Jakobs T, Herzog P, Schaller S, Nikolaou K, Suess C, et al. Aorto-iliac multidetector-row CT angiography with low kV settings: improved vessel enhancement and simultaneous reduction of radiation dose. Eur Radiol. 2005; 15(2): 334-41[DOI][PubMed]
  • 2. Heyer CM, Mohr PS, Lemburg SP, Peters SA, Nicolas V. Image quality and radiation exposure at pulmonary CT angiography with 100- or 120-kVp protocol: prospective randomized study. Radiology. 2007; 245(2): 577-83[DOI][PubMed]
  • 3. Napoli A, Fleischmann D, Chan FP, Catalano C, Hellinger JC, Passariello R, et al. Computed tomography angiography: state-of-the-art imaging using multidetector-row technology. J Comput Assist Tomogr. 2004; 28 Suppl 1-45[PubMed]
  • 4. Smith-Bindman R, Lipson J, Marcus R, Kim KP, Mahesh M, Gould R, et al. Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med. 2009; 169(22): 2078-86[DOI][PubMed]
  • 5. Cademartiri F, Nieman K, van der Lugt A, Raaijmakers RH, Mollet N, Pattynama PM, et al. Intravenous contrast material administration at 16-detector row helical CT coronary angiography: test bolus versus bolus-tracking technique. Radiology. 2004; 233(3): 817-23[DOI][PubMed]
  • 6. Fleischmann D. Use of high concentration contrast media: principles and rationale-vascular district. Eur J Radiol. 2003; 45 Suppl 1-93[PubMed]
  • 7. Foley WD, Karcaaltincaba M. Computed tomography angiography: principles and clinical applications. J Comput Assist Tomogr. 2003; 27 Suppl 1-30[PubMed]
  • 8. Nakajima Y, Yoshimine T, Yoshida H, Sakashita K, Okamoto M, Kishikawa M, et al. Computerized tomography angiography of ruptured cerebral aneurysms: factors affecting time to maximum contrast concentration. J Neurosurg. 1998; 88(4): 663-9[DOI][PubMed]
  • 9. McCollough CH, Leng S, Yu L, Cody DD, Boone JM, McNitt-Gray MF. CT dose index and patient dose: they are not the same thing. Radiology. 2011; 259(2): 311-6[DOI][PubMed]
  • 10. Cademartiri F, van der Lugt A, Luccichenti G, Pavone P, Krestin GP. Parameters affecting bolus geometry in CTA: a review. J Comput Assist Tomogr. 2002; 26(4): 598-607[PubMed]
  • 11. Sandstede JJ, Tschammler A, Beer M, Vogelsang C, Wittenberg G, Hahn D. Optimization of automatic bolus tracking for timing of the arterial phase of helical liver CT. Eur Radiol. 2001; 11(8): 1396-400[DOI][PubMed]
  • 12. Awai K, Hori S. Effect of contrast injection protocol with dose tailored to patient weight and fixed injection duration on aortic and hepatic enhancement at multidetector-row helical CT. Eur Radiol. 2003; 13(9): 2155-60[DOI][PubMed]
  • 13. Bae KT, Heiken JP, Brink JA. Aortic and hepatic peak enhancement at CT: effect of contrast medium injection rate--pharmacokinetic analysis and experimental porcine model. Radiology. 1998; 206(2): 455-64[DOI][PubMed]
  • 14. Kim T, Murakami T, Takahashi S, Tsuda K, Tomoda K, Narumi Y, et al. Effects of injection rates of contrast material on arterial phase hepatic CT. AJR Am J Roentgenol. 1998; 171(2): 429-32[DOI][PubMed]
  • 15. Zondervan RL, Hahn PF, Sadow CA, Liu B, Lee SI. Frequent body CT scanning of young adults: indications, outcomes, and risk for radiation-induced cancer. J Am Coll Radiol. 2011; 8(7): 501-7[DOI][PubMed]
  • 16. Sodickson A, Baeyens PF, Andriole KP, Prevedello LM, Nawfel RD, Hanson R, et al. Recurrent CT, cumulative radiation exposure, and associated radiation-induced cancer risks from CT of adults. Radiology. 2009; 251(1): 175-84[DOI][PubMed]
  • 17. Brenner DJ, Hall EJ. Computed tomography--an increasing source of radiation exposure. N Engl J Med. 2007; 357(22): 2277-84[DOI][PubMed]
  • 18. Schueller-Weidekamm C, Schaefer-Prokop CM, Weber M, Herold CJ, Prokop M. CT angiography of pulmonary arteries to detect pulmonary embolism: improvement of vascular enhancement with low kilovoltage settings. Radiology. 2006; 241(3): 899-907[DOI][PubMed]
  • 19. Behrendt FF, Bruners P, Keil S, Plumhans C, Mahnken AH, Das M, et al. Effect of different saline chaser volumes and flow rates on intravascular contrast enhancement in CT using a circulation phantom. Eur J Radiol. 2010; 73(3): 688-93[DOI][PubMed]
  • 20. Szucs-Farkas Z, Strautz T, Patak MA, Kurmann L, Vock P, Schindera ST. Is body weight the most appropriate criterion to select patients eligible for low-dose pulmonary CT angiography? Analysis of objective and subjective image quality at 80 kVp in 100 patients. Eur Radiol. 2009; 19(8): 1914-22[DOI][PubMed]
  • 21. Haage P, Schmitz-Rode T, Hubner D, Piroth W, Gunther RW. Reduction of contrast material dose and artifacts by a saline flush using a double power injector in helical CT of the thorax. AJR Am J Roentgenol. 2000; 174(4): 1049-53[DOI][PubMed]
  • 22. Huda W, Mettler FA. Volume CT dose index and dose-length product displayed during CT: what good are they? Radiology. 2011; 258(1): 236-42[DOI][PubMed]
  • 23. Christner JA, Kofler JM, McCollough CH. Estimating effective dose for CT using dose-length product compared with using organ doses: consequences of adopting International Commission on Radiological Protection publication 103 or dual-energy scanning. AJR Am J Roentgenol. 2010; 194(4): 881-9[DOI][PubMed]
  • 24. Boetticher H, Lachmund J, Looe HK, Hoffmann W, Poppe B. 2007 recommendations of the ICRP change basis for estimation of the effective dose: what is the impact on radiation dose assessment of patient and personnel? Rofo. 2008; 180(5): 391-5[DOI][PubMed]
  • 25. Yanaga Y, Awai K, Nakaura T, Utsunomiya D, Funama Y, Date S, et al. Hepatocellular carcinoma in patients weighing 70 kg or less: initial trial of compact-bolus dynamic CT with low-dose contrast material at 80 kVp. AJR Am J Roentgenol. 2011; 196(6): 1324-31[DOI][PubMed]
  • 26. Hoffmann MH, Shi H, Manzke R, Schmid FT, De Vries L, Grass M, et al. Noninvasive coronary angiography with 16-detector row CT: effect of heart rate. Radiology. 2005; 234(1): 86-97[DOI][PubMed]
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