Iranian Journal of Radiology

Published by: Kowsar

Embolization of Intracranial Arteriovenous Malformations Using Onyx in 53 Patients

Ahmad Aoude 1 , 2 , Hossein Ghanaati 1 , Morteza Faghih Jouibari 3 , * , Madjid Shakiba 1 , Mehdi Khaleghi 3 and Abbas Nowrouzi 4
Authors Information
1 Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran
2 International Campus, Tehran University of Medical Sciences, Tehran, Iran
3 Department of Neurosurgery, Tehran University of Medical Sciences, Tehran, Iran
4 Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran
Article information
  • Iranian Journal of Radiology: July 2017, 14 (3); e37696
  • Published Online: September 21, 2016
  • Article Type: Research Article
  • Received: March 9, 2016
  • Revised: July 3, 2016
  • Accepted: September 13, 2016
  • DOI: 10.5812/iranjradiol.37696

To Cite: Aoude A, Ghanaati H, Faghih Jouibari M, Shakiba M, Khaleghi M, et al. Embolization of Intracranial Arteriovenous Malformations Using Onyx in 53 Patients, Iran J Radiol. 2017 ; 14(3):e37696. doi: 10.5812/iranjradiol.37696.

Copyright © 2016, Tehran University of Medical Sciences and Iranian Society of Radiology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Crawford PM, West CR, Chadwick DW, Shaw MD. Arteriovenous malformations of the brain: natural history in unoperated patients. J Neurol Neurosurg Psychiatry. 1986; 49(1): 1-10[PubMed]
  • 2. Laakso A, Hernesniemi J. Arteriovenous malformations: epidemiology and clinical presentation. Neurosurg Clin N Am. 2012; 23(1): 1-6[DOI][PubMed]
  • 3. Ondra SL, Troupp H, George ED, Schwab K. The natural history of symptomatic arteriovenous malformations of the brain: a 24-year follow-up assessment. J Neurosurg. 1990; 73(3): 387-91[DOI][PubMed]
  • 4. Spetzler RF, Martin NA. A proposed grading system for arteriovenous malformations. J Neurosurg. 1986; 65(4): 476-83[DOI][PubMed]
  • 5. Hofmeister C, Stapf C, Hartmann A, Sciacca RR, Mansmann U, terBrugge K, et al. Demographic, morphological, and clinical characteristics of 1289 patients with brain arteriovenous malformation. Stroke. 2000; 31(6): 1307-10[PubMed]
  • 6. Yamashita K, Taki W, Iwata H, Nakahara I, Nishi S, Sadato A, et al. Characteristics of ethylene vinyl alcohol copolymer (EVAL) mixtures. AJNR Am J Neuroradiol. 1994; 15(6): 1103-5[PubMed]
  • 7. Terada T, Nakamura Y, Nakai K, Tsuura M, Nishiguchi T, Hayashi S, et al. Embolization of arteriovenous malformations with peripheral aneurysms using ethylene vinyl alcohol copolymer. Report of three cases. J Neurosurg. 1991; 75(4): 655-60[DOI][PubMed]
  • 8. Alexander MJ, Tolbert ME. Targeting cerebral arteriovenous malformations for minimally invasive therapy. Neurosurgery. 2006; 59(5 Suppl 3)-83[DOI][PubMed]
  • 9. Gao K, Yang XJ, Mu SQ, Li YX, Zhang YP, Lu M, et al. Embolization of brain arteriovenous malformations with ethylene vinyl alcohol copolymer: technical aspects. Chin Med J (Engl). 2009; 122(16): 1851-6[PubMed]
  • 10. Xu F, Ni W, Liao Y, Gu Y, Xu B, Leng B, et al. Onyx embolization for the treatment of brain arteriovenous malformations. Acta Neurochir (Wien). 2011; 153(4): 869-78[DOI][PubMed]
  • 11. Pierot L, Januel AC, Herbreteau D, Barreau X, Drouineau J, Berge J, et al. Endovascular treatment of brain arteriovenous malformations using Onyx: preliminary results of a prospective multicenter study. Intervent Neuroradiol. 2005; 11(1 suppl): 159-64
  • 12. Jahan R, Murayama Y, Gobin YP, Duckwiler GR, Vinters HV, Viñuela F. Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patients. Neurosurg. 2001; 48(5): 984-97
  • 13. Panagiotopoulos V, Gizewski E, Asgari S, Regel J, Forsting M, Wanke I. Embolization of intracranial arteriovenous malformations with ethylene-vinyl alcohol copolymer (Onyx). AJNR Am J Neuroradiol. 2009; 30(1): 99-106[DOI][PubMed]
  • 14. Strauss I, Frolov V, Buchbut D, Gonen L, Maimon S. Critical appraisal of endovascular treatment of brain arteriovenous malformation using Onyx in a series of 92 consecutive patients. Acta Neurochir (Wien). 2013; 155(4): 611-7[DOI][PubMed]
  • 15. Elsenousi A, Aletich VA, Alaraj A. Neurological outcomes and cure rates of embolization of brain arteriovenous malformations with n-butyl cyanoacrylate or Onyx: a meta-analysis. J Neurointerv Surg. 2016; 8(3): 265-72[DOI][PubMed]
  • 16. Friedlander RM. Clinical practice. Arteriovenous malformations of the brain. N Engl J Med. 2007; 356(26): 2704-12[DOI][PubMed]
  • 17. Arteriovenous malformations of the brain in adults. N Engl J Med. 1999; 340(23): 1812-8[DOI][PubMed]
  • 18. Baharvahdat H, Blanc R, Termechi R, Pistocchi S, Bartolini B, Redjem H, et al. Hemorrhagic complications after endovascular treatment of cerebral arteriovenous malformations. AJNR Am J Neuroradiol. 2014; 35(5): 978-83[DOI][PubMed]
  • 19. van Beijnum J, van der Worp HB, Buis DR, Al-Shahi Salman R, Kappelle LJ, Rinkel GJ, et al. Treatment of brain arteriovenous malformations: a systematic review and meta-analysis. JAMA. 2011; 306(18): 2011-9[DOI][PubMed]
  • 20. Hartmann A, Pile-Spellman J, Stapf C, Sciacca RR, Faulstich A, Mohr JP, et al. Risk of endovascular treatment of brain arteriovenous malformations. Stroke. 2002; 33(7): 1816-20[PubMed]
  • 21. Taylor CL, Dutton K, Rappard G, Pride GL, Replogle R, Purdy PD, et al. Complications of preoperative embolization of cerebral arteriovenous malformations. J Neurosurg. 2004; 100(5): 810-2[DOI][PubMed]
  • 22. Kemerink GJ, Frantzen MJ, Oei K, Sluzewski M, van Rooij WJ, Wilmink J, et al. Patient and occupational dose in neurointerventional procedures. Neuroradiology. 2002; 44(6): 522-8[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments