Iranian Journal of Radiology

Published by: Kowsar

Assessment of Independent Risk Factors of Developing Pneumothorax During Percutaneous Core Needle Lung Biopsy: Focus on Lesion Depth

Ha-Yeon Lee 1 and In Jae Lee 1 , *
Authors Information
1 Department of Radiology, Hallym University College of Medicine, Gyeonggi-do, Republic of Korea
Article information
  • Iranian Journal of Radiology: October 01, 2016, 13 (4); e30929
  • Published Online: July 4, 2016
  • Article Type: Research Article
  • Received: June 24, 2015
  • Revised: November 5, 2015
  • Accepted: November 24, 2015
  • DOI: 10.5812/iranjradiol.30929

To Cite: Lee H, Lee I J. Assessment of Independent Risk Factors of Developing Pneumothorax During Percutaneous Core Needle Lung Biopsy: Focus on Lesion Depth, Iran J Radiol. 2016 ; 13(4):e30929. doi: 10.5812/iranjradiol.30929.

Copyright © 2016, Tehran University of Medical Sciences and Iranian Society of Radiology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Lee IJ, Bae YA, Kim DG, Jung KS, Im HJ, Lee K, et al. Percutaneous needle aspiration biopsy (PCNAB) of lung lesions: 5 years results with focusing on repeat PCNAB. Eur J Radiol. 2010; 73(3): 551-4[DOI][PubMed]
  • 2. Geraghty PR, Kee ST, McFarlane G, Razavi MK, Sze DY, Dake MD. CT-guided transthoracic needle aspiration biopsy of pulmonary nodules: needle size and pneumothorax rate. Radiology. 2003; 229(2): 475-81[DOI][PubMed]
  • 3. Tomiyama N, Yasuhara Y, Nakajima Y, Adachi S, Arai Y, Kusumoto M, et al. CT-guided needle biopsy of lung lesions: a survey of severe complication based on 9783 biopsies in Japan. Eur J Radiol. 2006; 59(1): 60-4[DOI][PubMed]
  • 4. Richardson CM, Pointon KS, Manhire AR, Macfarlane JT. Percutaneous lung biopsies: a survey of UK practice based on 5444 biopsies. Br J Radiol. 2002; 75(897): 731-5[DOI][PubMed]
  • 5. Kazerooni EA, Lim FT, Mikhail A, Martinez FJ. Risk of pneumothorax in CT-guided transthoracic needle aspiration biopsy of the lung. Radiology. 1996; 198(2): 371-5[DOI][PubMed]
  • 6. Laurent F, Michel P, Latrabe V, Tunon de Lara M, Marthan R. Pneumothoraces and chest tube placement after CT-guided transthoracic lung biopsy using a coaxial technique: incidence and risk factors. AJR Am J Roentgenol. 1999; 172(4): 1049-53[DOI][PubMed]
  • 7. Saji H, Nakamura H, Tsuchida T, Tsuboi M, Kawate N, Konaka C, et al. The incidence and the risk of pneumothorax and chest tube placement after percutaneous CT-guided lung biopsy: the angle of the needle trajectory is a novel predictor. Chest. 2002; 121(5): 1521-6[PubMed]
  • 8. Ko JP, Shepard JO, Drucker EA, Aquino SL, Sharma A, Sabloff B, et al. Factors influencing pneumothorax rate at lung biopsy: are dwell time and angle of pleural puncture contributing factors? Radiology. 2001; 218(2): 491-6[DOI][PubMed]
  • 9. Cox JE, Chiles C, McManus CM, Aquino SL, Choplin RH. Transthoracic needle aspiration biopsy: variables that affect risk of pneumothorax. Radiology. 1999; 212(1): 165-8[DOI][PubMed]
  • 10. Fish GD, Stanley JH, Miller KS, Schabel SI, Sutherland SE. Postbiopsy pneumothorax: estimating the risk by chest radiography and pulmonary function tests. AJR Am J Roentgenol. 1988; 150(1): 71-4[DOI][PubMed]
  • 11. vanSonnenberg E, Casola G, Ho M, Neff CC, Varney RR, Wittich GR, et al. Difficult thoracic lesions: CT-guided biopsy experience in 150 cases. Radiology. 1988; 167(2): 457-61[DOI][PubMed]
  • 12. Poe RH, Kallay MC, Wicks CM, Odoroff CL. Predicting risk of pneumothorax in needle biopsy of the lung. Chest. 1984; 85(2): 232-5[PubMed]
  • 13. Miller KS, Fish GB, Stanley JH, Schabel SI. Prediction of pneumothorax rate in percutaneous needle aspiration of the lung. Chest. 1988; 93(4): 742-5[PubMed]
  • 14. Hiraki T, Mimura H, Gobara H, Shibamoto K, Inoue D, Matsui Y, et al. Incidence of and risk factors for pneumothorax and chest tube placement after CT fluoroscopy-guided percutaneous lung biopsy: retrospective analysis of the procedures conducted over a 9-year period. AJR Am J Roentgenol. 2010; 194(3): 809-14[DOI][PubMed]
  • 15. Yeow KM, See LC, Lui KW, Lin MC, Tsao TC, Ng KF, et al. Risk factors for pneumothorax and bleeding after CT-guided percutaneous coaxial cutting needle biopsy of lung lesions. J Vasc Interv Radiol. 2001; 12(11): 1305-12[PubMed]
  • 16. Yeow KM, Su IH, Pan KT, Tsay PK, Lui KW, Cheung YC, et al. Risk factors of pneumothorax and bleeding: multivariate analysis of 660 CT-guided coaxial cutting needle lung biopsies. Chest. 2004; 126(3): 748-54[DOI][PubMed]
  • 17. Covey AM, Gandhi R, Brody LA, Getrajdman G, Thaler HT, Brown KT. Factors associated with pneumothorax and pneumothorax requiring treatment after percutaneous lung biopsy in 443 consecutive patients. J Vasc Interv Radiol. 2004; 15(5): 479-83[PubMed]
  • 18. Topal U, Ediz B. Transthoracic needle biopsy: factors effecting risk of pneumothorax. Eur J Radiol. 2003; 48(3): 263-7[PubMed]
  • 19. Anderson JM, Murchison J, Patel D. CT-guided lung biopsy: factors influencing diagnostic yield and complication rate. Clin Radiol. 2003; 58(10): 791-7[PubMed]
  • 20. Collings CL, Westcott JL, Banson NL, Lange RC. PneumothADDIN EN.CITE.DATAorax and dependent versus nondependent patient position after needle biopsy of the lung. Radiology. 1999; 210(1): 59-64[DOI][PubMed]
  • 21. Choi CM, Um SW, Yoo CG, Kim YW, Han SK, Shim YS, et al. Incidence and risk factors of delayed pneumothorax after transthoracic needle biopsy of the lung. Chest. 2004; 126(5): 1516-21[DOI][PubMed]
  • 22. Yildirim E, Kirbas I, Harman A, Ozyer U, Tore HG, Aytekin C, et al. CT-guided cutting needle lung biopsy using modified coaxial technique: factors effecting risk of complications. Eur J Radiol. 2009; 70(1): 57-60[DOI][PubMed]
  • 23. Chakrabarti B, Earis JE, Pandey R, Jones Y, Slaven K, Amin S, et al. Risk assessment of pneumothorax and pulmonary haemorrhage complicating percutaneous co-axial cutting needle lung biopsy. Respir Med. 2009; 103(3): 449-55[DOI][PubMed]
  • 24. Khan MF, Straub R, Moghaddam SR, Maataoui A, Gurung J, Wagner TO, et al. Variables affecting the risk of pneumothorax and intrapulmonal hemorrhage in CT-guided transthoracic biopsy. Eur Radiol. 2008; 18(7): 1356-63[DOI][PubMed]
  • 25. Ohno Y, Hatabu H, Takenaka D, Higashino T, Watanabe H, Ohbayashi C, et al. CT-guided transthoracic needle aspiration biopsy of small (< or = 20 mm) solitary pulmonary nodules. AJR Am J Roentgenol. 2003; 180(6): 1665-9[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .
Readers' Comments