Iranian Journal of Radiology

Published by: Kowsar

Atypical Findings of Focal Nodular Hyperplasia with Gadoxetic Acid (Gd-EOB-DTPA)-Enhanced Magnetic Resonance Imaging

Jung-Hee Yoon 1 , * and Ji-Yeon Kim 2
Authors Information
1 Department of Radiology, Haeundae Paik Hospital, Inje University College of Medicine, Jwa-dong, Haeundae-gu, Busan, Korea
2 Department of Pathology, Haeundae Paik Hospital, Inje University College of Medicine, Jwa-dong, Haeundae-gu, Busan, Korea
Article information
  • Iranian Journal of Radiology: January 01, 2014, 11 (1); e9269
  • Published Online: January 28, 2014
  • Article Type: Case Report
  • Received: November 26, 2012
  • Revised: February 23, 2013
  • Accepted: June 26, 2013
  • DOI: 10.5812/iranjradiol.9269

To Cite: Yoon J, Kim J. Atypical Findings of Focal Nodular Hyperplasia with Gadoxetic Acid (Gd-EOB-DTPA)-Enhanced Magnetic Resonance Imaging, Iran J Radiol. 2014 ; 11(1):e9269. doi: 10.5812/iranjradiol.9269.

Copyright © 2014, Tehran University of Medical Sciences and Iranian Society of Radiology. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case presentation
3. Discussion
  • 1. Maillette de Buy Wenniger L, Terpstra V, Beuers U. Focal nodular hyperplasia and hepatic adenoma: epidemiology and pathology. Dig Surg. 2010; 27(1): 24-31[DOI][PubMed]
  • 2. Cho SW, Marsh JW, Steel J, Holloway SE, Heckman JT, Ochoa ER, et al. Surgical management of hepatocellular adenoma: take it or leave it? Ann Surg Oncol. 2008; 15(10): 2795-803[DOI][PubMed]
  • 3. Grazioli L, Morana G, Federle MP, Brancatelli G, Testoni M, Kirchin MA, et al. Focal nodular hyperplasia: morphologic and functional information from MR imaging with gadobenate dimeglumine. Radiol. 2001; 221(3): 731-9[DOI][PubMed]
  • 4. Huppertz A, Haraida S, Kraus A, Zech CJ, Scheidler J, Breuer J, et al. Enhancement of focal liver lesions at gadoxetic acid-enhanced MR imaging: correlation with histopathologic findings and spiral CT--initial observations. Radiol. 2005; 234(2): 468-78[DOI][PubMed]
  • 5. Ko KR, Lee DH, Park JS, Yi BH, Lim JW, Ko YT, et al. Focal nodular hyperplasia with retraction of liver capsule: a case report. Korean J Radiol. 2003; 4(1): 66-9[PubMed]
  • 6. Federle MP, Brancatelli G. Imaging of benign hepatic masses. Semin Liver Dis. 2001; 21(2): 237-49[DOI][PubMed]
  • 7. Trotter JamesF, Everson GregoryT. Benign Focal Lesions of the Liver. Cl Liver Dis. 2001; 5(1): 17-42[DOI]
  • 8. Wanless IR, Mawdsley C, Adams R. On the pathogenesis of focal nodular hyperplasia of the liver. Hepatology. 1985; 5(6): 1194-200[PubMed]
  • 9. Choi JY, Lee HC, Yim JH, Shim JH, Lim YS, Shin YM, et al. Focal nodular hyperplasia or focal nodular hyperplasia-like lesions of the liver: a special emphasis on diagnosis. J Gastroenterol Hepatol. 2011; 26(6): 1004-9[DOI][PubMed]
  • 10. Shortell CK, Schwartz SI. Hepatic adenoma and focal nodular hyperplasia. Surg Gynecol Obstet. 1991; 173(5): 426-31[PubMed]
  • 11. Mergo PJ, Ros PR. Benign Lesions of the Liver Radiol Cl North America. 1998; 36(2): 319-331[DOI]
  • 12. Shamsi K, De Schepper A, Degryse H, Deckers F. Focal nodular hyperplasia of the liver: radiologic findings. Abdom Imaging. 1993; 18(1): 32-8[PubMed]
  • 13. Kehagias D, Moulopoulos L, Antoniou A, Hatziioannou A, Smyrniotis V, Trakadas S, et al. Focal nodular hyperplasia: imaging findings. Eur Radiol. 2001; 11(2): 202-12[PubMed]
  • 14. Mortele KJ, Praet M, Van Vlierberghe H, Kunnen M, Ros PR. CT and MR imaging findings in focal nodular hyperplasia of the liver: radiologic-pathologic correlation. AJR Am J Roentgenol. 2000; 175(3): 687-92[DOI][PubMed]
  • 15. Zech CJ, Grazioli L, Breuer J, Reiser MF, Schoenberg SO. Diagnostic performance and description of morphological features of focal nodular hyperplasia in Gd-EOB-DTPA-enhanced liver magnetic resonance imaging: results of a multicenter trial. Invest Radiol. 2008; 43(7): 504-11[DOI][PubMed]
  • 16. Sherman M. The radiological diagnosis of hepatocellular carcinoma. Am J Gastroenterol. 2010; 105(3): 610-2[DOI][PubMed]
  • 17. Fukukura Yoshihiko, Nakashima Osamu, Kusaba Akiko, Kage Masayoshi, Kojiro Masamichi. Angioarchitecture and blood circulation in focal nodular hyperplasia of the liver. J hepatology. 1998; 29(3): 470-475
  • 18. Choi CS, Freeny PC. Triphasic helical CT of hepatic focal nodular hyperplasia: incidence of atypical findings. AJR Am J Roentgenol. 1998; 170(2): 391-5[DOI][PubMed]
  • 19. Fujiwara H, Sekine S, Onaya H, Shimada K, Mikata R, Arai Y. Ring-like enhancement of focal nodular hyperplasia with hepatobiliary-phase Gd-EOB-DTPA-enhanced magnetic resonance imaging: radiological-pathological correlation. Jpn J Radiol. 2011; 29(10): 739-43[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .
Readers' Comments